Search for:

Publications

Peer-reviewed journal research and review articles

Publications by year: Prior to 2026 | 2026

2026

Prior to 2026 (*denotes co-first author)

  1. Li X, Zhao Y, Hsu JC, Sarduy EA, Barnhart TE, Engle JW, Wei W, Hu S, Cai W. [44Sc]Sc-CHX-A″-DTPA-RCCB6: a PET tracer for imaging CD70 expression across latency types of Burkitt lymphoma. J Nucl Med. 2025. doi: 10.2967/jnumed.125.269991.
  2. Huang W*, Chao F*, Hsu JC*, Sun X, Barnhart TE, Engle JW, Han X, Kang L, Cai W. Noninvasive immunoPET imaging of PD-L1 expression in non-small cell lung cancer and bladder cancer using [89Zr]Zr-DFO-Durvalumab. Colloids Surf A: Physicochem Eng Asp. 2025, 723:137332. doi: 10.1016/j.colsurfa.2025.137332.
  3. Liu P, Zhou M, Luo Z, Hao L, Hsu JC, Cai W, Zhou W, Hu S. A 177Lu-nucleotide coordination polymer-incorporated thermosensitive hydrogel with anti-inflammatory and chondroprotective capabilities for osteoarthritis treatment. Biomaterials. 2025, 317:123098. doi: 10.1016/j.biomaterials.2025.123098.
  4. Huang W, Liu Y, Li R, Yang Y, Hsu JC, DeLuca MC, Engle JW, Wei Y, Kang L, Li L, Cai W. [64Cu]Cu-NOTA-Ivonescimab: a novel PET tracer for imaging VEGF expression in colorectal carcinoma. Biophys Rep. 2025. doi: 10.52601/bpr.2025.250031.
  5. Liu P, Hao L, Hsu JC, Zhou M, Luo Z, Peng Y, Cai W, Hu S. Biomineralized nanocomposite-integrated microneedle patch for combined brachytherapy and photothermal therapy in postoperative melanoma recurrence and infectious wound healing. Adv Sci. 2025, e2414468. doi: 10.1002/advs.202414468.
  6. Huang W, Li L, Chao F, Yang Q, Mixdorf JC, Engle JW, Hsu JC, Kang L, Cai W. [64Cu]Cu-NOTA-EV-F(ab’)2 enables same-day immuno-pet imaging of Nectin-4 in triple-negative breast and urothelial bladder cancers. J Nucl Med. 2025. doi: 10.2967/jnumed.125.270132.
  7. Mossburg KJ, Shepherd SJ, Barragan D, O NH, Berkow EK, Maidment PSN, Rosario Berrios DN, Hsu JC, Siedlik MJ, Yadavali S, Mitchell MJ, Issadore D, Cormode DP. Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip. Eur J Nucl Med Mol Imaging. 2025, 52(3):1177-1188. doi: 10.1007/s00259-024-06967-5.
  8. Huang W, Li L, Zhou Y, Yang Q, Mixdorf JC, Barnhart TE, Hsu JC, Saladin RJ, Liu C, Rosenkrans ZT, Engle JW, Gao J, Kang L, Cai W. Preclinical evaluation of zirconium-89 labeled anti-Trop2 antibody-drug conjugate (Trodelvy) for imaging in gastric cancer and triple-negative breast cancer. Eur J Nucl Med Mol Imaging. 2025. doi: 10.1007/s00259-025-07106-4.
  9. Huang W, Sun X, Li X, Hsu JC, Qiu Y, DeLuca MC, Engle JW, Li L, Lu J, Wang T, Kang L, Cai W. Rapid and specific immunoPET imaging of Nectin-4 in gastric cancer and non-small cell lung cancer using [64Cu]Cu-NOTA-EV-F(ab’)2. Eur J Nucl Med Mol Imaging. 2025. doi: 10.1007/s00259-025-07402-z.
  10. Huang W, Zhou J, Liu Y, Yang Y, Saladin RJ, Hsu JC, Cai W, Kang L. Advances in immunoPET/SPECT imaging: the role of Fab and F(ab’)2 fragments in theranostics. Acta Pharm Sin B. 2025, 15(8):3888-3924. doi: 10.1016/j.apsb.2025.05.030.
  11. Liu P, Zhao Y, Peng Y, Hsu JC, Zhou M, Zhou W, Hu S, Cai W. Harnessing the power of nanoagents in acute kidney injury: a versatile platform for imaging and treatment. Coord Chem Rev. 2025, 533:216570. doi: 10.1016/j.ccr.2025.216570.
  12. Zhou J, Ji X, Wang H, Hsu JC, Hua C, Yang X, Liu Z, Guo H, Huang Y, Li Y, Cai W, Lin X, Ni D. Design of ultrasound-driven charge interference therapy for wound infection. Nano Lett. 2024, 24(26):7868-7878. doi: 10.1021/acs.nanolett.4c00930.
  13. Hsu JC*, Lau KC*, Barragan D, Mossburg KJ, Cormode DP, Maidment ADA. Influence of acquisition parameters on silver sulfide nanoparticle contrast in photon-counting digital mammography: a phantom study. ACS Appl Nano Mater. 2024, 7(5): 4805-4813. doi: 10.1021/acsanm.3c05431.
  14. Tang Z, Yu F, Hsu JC, Shi J, Cai W. Soybean oil-derived lipids for efficient mRNA delivery. Adv Mater. 2024, 36(13):e2302901. doi: 10.1002/adma.202302901.
  15. Hsu JC, Barragan D, Tward AE, Hajfathalian M, Amirshaghaghi A, Mossburg KJ, Rosario-Berríos DN, Bouché M, Andrianov AK, Delikatny EJ, Cormode DP. A biodegradable “one-for-all” nanoparticle for multimodality imaging and enhanced photothermal treatment of breast cancer. Adv Healthc Mater. 2024, 13(8):e2303018. doi: 10.1002/adhm.202303018.
  16. Liu Y, Huang W, Saladin RJ, Hsu JC, Cai W, Kang L. Trop2-targeted molecular imaging in solid tumors: current advances and future outlook. Mol Pharm. 2024, 21(12):5909-5928. doi: 10.1021/acs.molpharmaceut.4c00848.
  17. Wang H*, Hsu JC*, Song W*, Lan X, Cai W, Ni D. Nanorepair medicine for treatment of organ injury. Natl Sci Rev. 2024, 11(9):nwae280. doi: 10.1093/nsr/nwae280.
  18. Hsu JC*, Liu P*, Song Y*, Song W, Saladin RJ, Peng Y, Hu S, Lan X, Cai W. Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond. Chem Soc Rev. 2024, 53(15):7657-7680. doi: 10.1039/d4cs00421c.
  19. Hu Q*, Zuo H*, Hsu JC*, Zeng C, Tian Z, Sun Z, Cai W, Tang Z, Chen W. The emerging landscape for combating resistance associated with energy-based therapies via nanomedicine. Adv Mater. 2024, 36(5):e2308286. doi: 10.1002/adma.202308286.
  20. Yan J, Tang Z, Li Y, Wang H, Hsu JC, Shi M, Fu Z, Ji X, Cai W, Ni D, Qu J. Molybdenum nanodots for acute lung injury therapy. ACS Nano. 2023, 17(23):23872-23888. doi: 10.1021/acsnano.3c08147.
  21. Dong YC, Nieves LM, Hsu JC, Kumar A, Bouché M, Krishnan U, Mossburg KJ, Saxena D, Uman S, Kambayashi T, Burdick JA, Kim MM, Dorsey JF, Cormode DP. Novel combination treatment for melanoma: FLASH radiotherapy and immunotherapy delivered by a radiopaque and radiation responsive hydrogel. Chem Mater. 2023, 35(22):9542-9551. doi: 10.1021/acs.chemmater.3c01390.
  22. Hajfathalian M, de Vries CR, Hsu JC, Amirshaghaghi A, Dong YC, Ren Z, Liu Y, Huang Y, Li Y, Knight SA, Jonnalagadda P, Zlitni A, Grice EA, Bollyky PL, Koo H, Cormode DP. Theranostic gold-in-gold cage nanoparticles enable photothermal ablation and photoacoustic imaging in biofilm-associated infection models. J Clin Invest. 2023, 133(21):e168485. doi: 10.1172/JCI168485.
  23. Ji X, Zhu L, Hsu JC, Wang H, Zhou J, Wang Q, Li Y, Cai W, Ni D, Wu Z. Tungsten-based nanoparticles as contrast agents for liver tumor detection using dual-energy computed tomography. Biomater Sci. 2023, 11(24):7817-7825. doi: 10.1039/d3bm01068f.
  24. Huang Y, Liu Y, Pandey NK, Shah S, Simon-Soro A, Hsu JC, Ren Z, Xiang Z, Kim D, Ito T, Oh MJ, Buckley C, Alawi F, Li Y, Smeets PJM, Boyer S, Zhao X, Joester D, Zero DT, Cormode DP, Koo H. Iron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention. Nat Commun. 2023, 14(1):6087. doi: 10.1038/s41467-023-41687-8.
  25. Ghosh S, Lee SJ, Hsu JC, Chakraborty S, Chakravarty R, Cai W. Cancer brachytherapy at the nanoscale: an emerging paradigm. Chem Biomed Imaging. 2023, 2(1):4-26. doi: 10.1021/cbmi.3c00092.
  26. Xu Y*, Hsu JC*, Xu L, Chen W, Cai W, Wang K. Nanomedicine-based adjuvant therapy: a promising solution for lung cancer. J Nanobiotechnology. 2023, 21(1):211. doi: 10.1186/s12951-023-01958-4.
  27. Yang Q, Huang W, Hsu JC, Song L, Sun X, Li C, Cai W, Kang L. CD146-targeted nuclear medicine imaging in cancer: state of the art. View. 2023, 4(5):20220085. doi: 10.1002/VIW.20220085.
  28. Zhu T*, Hsu JC*, Guo J, Chen W, Cai W, Wang K. Radionuclide-based theranostics – a promising strategy for lung cancer. Eur J Nucl Med Mol Imaging. 2023, 50(8):2353-2374. doi: 10.1007/s00259-023-06174-8.
  29. Rosenkrans ZT*, Hsu JC*, Aluicio-Sarduy E, Barnhart TE, Engle JW, Cai W. Amplification of Cerenkov luminescence using semiconducting polymers for cancer theranostics. Adv Funct Mater. 2023, 33(33):2302777. doi: 10.1002/adfm.202302777.
  30. Hsu JC, Tang Z, Eremina OE, Sofias AM, Lammers T, Lovell JF, Zavaleta C, Cai W, Cormode DP. Nanomaterial-based contrast agents. Nat Rev Methods Primers. 2023, 3:30. doi: 10.1038/s43586-023-00211-4.
  31. Dong YC, Kumar A, Rosario-Berríos DN, Si-Mohamed S, Hsu JC, Nieves LM, Douek P, Noël PB, Cormode DP. Ytterbium nanoparticle contrast agents for conventional and spectral photon-counting CT and their applications for hydrogel imaging. ACS Appl Mater Interfaces. 2022, 14(34):39274-39284. doi: 10.1021/acsami.2c12354.
  32. Nieves LM, Dong YC, Rosario-Berríos DN, Mossburg K, Hsu JC, Cramer GM, Busch TM, Maidment ADA, Cormode DP. Renally excretable silver telluride nanoparticles as contrast agents for X-ray imaging. ACS Appl Mater Interfaces. 2022, 14(30):34354-34364. doi: 10.1021/acsami.2c06190.
  33. Huang Y, Hsu JC, Koo H, Cormode DP. Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle. Theranostics. 2022, 12(2):796-816. doi: 10.7150/thno.67375.
  34. Kim J, Hong G, Mazaleuskaya L, Hsu JC, Rosario-Berrios DN, Grosser T, Cho-Park PF, Cormode DP. Ultrasmall antioxidant cerium oxide nanoparticles for regulation of acute inflammation. ACS Appl Mater Interfaces. 2021, 13(51):60852-60864. doi: 10.1021/acsami.1c16126.
  35. Hsu JC, Du Y, Sengupta A, Dong YC, Mossburg KJ, Bouché M, Maidment ADA, Weljie AM, Cormode DP. Effect of nanoparticle synthetic conditions on ligand coating integrity and subsequent nano-biointeractions. ACS Appl Mater Interfaces. 2021, 13(49):58401-58410. doi: 10.1021/acsami.1c18941.
  36. Bouché M, Dong YC, Sheikh S, Taing K, Saxena D, Hsu JC, Chen MH, Salinas RD, Song H, Burdick JA, Dorsey J, Cormode DP. Novel treatment for glioblastoma delivered by a radiation responsive and radiopaque hydrogel. ACS Biomater Sci Eng. 2021, 7(7):3209-3220. doi: 10.1021/acsbiomaterials.1c00385.
  37. Si-Mohamed SA, Sigovan M, Hsu JC, Tatard-Leitman V, Chalabreysse L, Naha PC, Garrivier T, Dessouky R, Carnaru M, Boussel L, Cormode DP, Douek PC. In vivo molecular K-edge imaging of atherosclerotic plaque using photon-counting CT. Radiology. 2021, 300(1):98-107. doi: 10.1148/radiol.2021203968.
  38. Nieves LM, Hsu JC, Lau KC, Maidment ADA, Cormode DP. Silver telluride nanoparticles as biocompatible and enhanced contrast agents for X-ray imaging: an in vivo breast cancer screening study. Nanoscale. 2021, 13(1):163-174. doi: 10.1039/d0nr05489e.
  39. Huang Y, Liu Y, Shah S, Kim D, Simon-Soro A, Ito T, Hajfathalian M, Li Y, Hsu JC, Nieves LM, Alawi F, Naha PC, Cormode DP, Koo H. Precision targeting of bacterial pathogen via bi-functional nanozyme activated by biofilm microenvironment. Biomaterials. 2021, 268:120581. doi: 10.1016/j.biomaterials.2020.120581.
  40. Nieves LM, Mossburg K, Hsu JC, Maidment ADA, Cormode DP. Silver chalcogenide nanoparticles: a review of their biomedical applications. Nanoscale. 2021, 13(46):19306-19323. doi: 10.1039/d0nr03872e.
  41. Naha PC, Hsu JC, Kim J, Shah S, Bouché M, Si-Mohamed S, Rosario-Berrios DN, Douek P, Hajfathalian M, Yasini P, Singh S, Rosen MA, Morgan MA, Cormode DP. Dextran-coated cerium oxide nanoparticles: a computed tomography contrast agent for imaging the gastrointestinal tract and inflammatory bowel disease. ACS Nano. 2020, 14(8):10187-10197. doi: 10.1021/acsnano.0c03457.
  42. Kim J, Silva AB, Hsu JC, Maidment PSN, Shapira N, Noël PB, Cormode DP. Radioprotective garment-inspired biodegradable polymetal nanoparticles for enhanced CT contrast production. Chem Mater. 2020, 32(1):381-391. doi: 10.1021/acs.chemmater.9b03931.
  43. Hsu JC, Nieves LM, Betzer O, Sadan T, Noël PB, Popovtzer R, Cormode DP. Nanoparticle contrast agents for X-ray imaging applications. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2020, 12(6):e1642. doi: 10.1002/wnan.1642. (Featured on Advanced Science News)
  44. Bouché M, Hsu JC, Dong YC, Kim J, Taing K, Cormode DP. Recent advances in molecular imaging with gold nanoparticles. Bioconjug Chem. 2020, 31(2):303-314. doi: 10.1021/acs.bioconjchem.9b00669.
  45. Dong YC, Hajfathalian M, Maidment PSN, Hsu JC, Naha PC, Si-Mohamed S, Breuilly M, Kim J, Chhour P, Douek P, Litt HI, Cormode DP. Effect of gold nanoparticle size on their properties as contrast agents for computed tomography. Sci Rep. 2019, 9(1):14912. doi: 10.1038/s41598-019-50332-8.
  46. Hsu JC, Cruz ED, Lau KC, Bouché M, Kim J, Maidment ADA, Cormode DP. Renally excretable and size-tunable silver sulfide nanoparticles for dual-energy mammography or computed tomography. Chem Mater. 2019, 31(19):7845-7854. doi: 10.1021/acs.chemmater.9b01750.
  47. Hajfathalian M, Amirshaghaghi A, Naha PC, Chhour P, Hsu JC, Douglas K, Dong Y, Sehgal CM, Tsourkas A, Neretina S, Cormode DP. Wulff in a cage gold nanoparticles as contrast agents for computed tomography and photoacoustic imaging. Nanoscale. 2018, 10(39):18749-18757. doi: 10.1039/c8nr05203d.
  48. Hsu JC, Naha PC, Lau KC, Chhour P, Hastings R, Moon BF, Stein JM, Witschey WRT, McDonald ES, Maidment ADA, Cormode DP. An all-in-one nanoparticle (AION) contrast agent for breast cancer screening with DEM-CT-MRI-NIRF imaging. Nanoscale. 2018, 10(36):17236-17248. doi: 10.1039/c8nr03741h.
  49. Morgan JIW, Vergilio GK, Hsu JC, Dubra A, Cooper RF. The reliability of cone density measurements in the presence of rods. Transl Vis Sci Technol. 2018, 7(3):21. doi: 10.1167/tvst.7.3.21.
  50. Kim J, Chhour P, Hsu JC, Litt HI, Ferrari VA, Popovtzer R, Cormode DP. Use of nanoparticle contrast agents for cell tracking with computed tomography. Bioconjug Chem. 2017, 28(6):1581-1597. doi: 10.1021/acs.bioconjchem.7b00194.
  51. Naha PC, Lau KC, Hsu JC, Hajfathalian M, Mian S, Chhour P, Uppuluri L, McDonald ES, Maidment AD, Cormode DP. Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography. Nanoscale. 2016, 8(28):13740-54. doi: 10.1039/c6nr02618d.
  52. Cheheltani R, Ezzibdeh RM, Chhour P, Pulaparthi K, Kim J, Jurcova M, Hsu JC, Blundell C, Litt HI, Ferrari VA, Allcock HR, Sehgal CM, Cormode DP. Tunable, biodegradable gold nanoparticles as contrast agents for computed tomography and photoacoustic imaging. Biomaterials. 2016, 102:87-97. doi: 10.1016/j.biomaterials.2016.06.015.