Novel radiotherapy treatment techniques

Spatially Fractionated Radiotherapy

Spatially fractionated radiotherapy (SFRT) delivers high doses of radiation to tumor regions while sparing healthy tissue. This approach holds promise for enhancing tumor control, but challenges remain. Precise targeting, optimal dosimetry, radiobiological responses, and potential side effects need comprehensive investigation to harness SFRT’s potential and advance cancer treatment.

Together with Dr. Scarpelli’s Lab, we are investigating the immunomodulatory and systemic effects of SFRT in a bit to comprehend the potential of SFRT and be able to leverage it.

Adaptive Radiotherapy

Adaptive radiotherapy is a dynamic approach that involves modifying treatment plans based on real-time patient anatomy changes or tumor characteristics. This technique aims to account for variations that can occur during radiation therapy, improving treatment accuracy and outcomes. However, implementing adaptive radiotherapy presents several challenges. These include the need for frequent imaging, accurate data interpretation, efficient plan adjustments, and seamless integration into clinical workflows. Addressing these challenges is essential to realize adaptive radiotherapy’s benefits and ensure its successful implementation in personalized cancer treatment.

We are working on developing tumor-tracking tools that can be used in real-time to guide radiotherapy delivery.