Chad Carroll

Areas of Expertise

• tendon physiology
• tendon pathology and healing
• diabetic tendinopathy
• muscle and tendon exercise adaptations

HHS Signature Research Area(s)

• Developmental Health and Wellness
• Healthy Lifestyles and Vital Longevity

Department of Health and Kinesiology Research Area(s)

• Exercise Physiology

Biography

Dr. Carroll’s academic work has molded an overall portfolio of research, teaching, and service around a central theme of tendon biology. The long-term goal of Dr. Carroll’s research is to determine the mechanisms contributing to poor tendon health and discover approaches to normalize tendon function. Tendon pathology (tendinopathies) affects 1 out of every 4 Americans with particularly high rates in person with diabetes. Tendinopathies lead to reduced quality of life and considerable economic burden. Dr. Carroll’s multi-faceted research portfolio has projects focused on endogenous circulating mediators of tendon pathology. This includes advanced glycation end-products (AGEs, which are elevated in persons with diabetes) and hormones such as estrogen. His work also focuses on nutritional interventions and how their combination with exercise can serve as a modifier for tendon health. Dr. Carroll’s work spans the translational spectrum – from molecular biology experiments to test mechanisms of disease to human clinical trials to test treatment efficacy. He has been supported by external grants from the National Institutes of Health and active clinical trial support from the National Cattleman’s Beef Association; internal grants from the Showalter Trust, the Indiana University Center for Diabetes and Metabolic Diseases, the Center for Aging and the Life Course, and the Indiana CTSI. Dr. Carroll has disseminated his research through both written and oral mediums. He has published 47 peer-reviewed manuscripts (19 in current rank at Purdue) and given numerous poster/podium/invited presentations at national meetings. His publications have been cited over 1800 times which represents an indication that his peers find this work to be advancing the field.

Education

• PhD, 2004, Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock
• MS, 2001, Exercise Physiology, Ball State University, Muncie, IN
• BS, 1999, Exercise Science, Lake Superior State University, Sault Ste. Marie, MI

Websites

• Linkedin

Current Courses

• HK368 - Exercise Physiology
• HK532 - Musculoskeletal Adaptations

Selected Grants

• Agency/Mechanism: 1 R01 AR081967-01 Title of Grant: Serum Advanced Glycation End-Products as Mediators of Tendon Degeneration with Diabetes. Duration of Funding: 09/25/2023-07/31/2028 Total Amount of Award: $3,066,018 Role: Principal Investigator
• Agency/Mechanism: National Cattlemen’s Beef Association Title of Grant: Effect of incorporating lean beef into a protein-rich diet during resistance training program on skeletal muscle and connective tissue strength and quality in older women. Duration of Funding: 03/01/2020 – 08/31/2022 Total Amount of Award: $324,442 Role: Principal Investigator

Professional Affiliations

• 2022-present, Section Member-At-Large Orthopaedic Research Society Tendon Research Section